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What Happens When You Mix Cocaine and Xanax?

Combining an upper like cocaine, and a downer like Xanax, gives off powerful effects that act as a push and pull or a high and low. These drugs in combination make you much more likely to develop-tolerance, dependence, and addiction while also being extremely addictive taken on their own. 

Continued abuse of Cocaine and Xanax together can result in severe depression, suicidal thoughts, morbid thoughts, suicide, and death. Because these two drugs have such opposing effects, there is a much higher risk for overdose and death when in use. 

Treatment for Cocaine and Xanax addiction requires detox, inpatient rehab, cognitive therapy, behavioural therapy, and 12 step programs. 

Mixing of Cocaine and Xanax?

Cocaine and Xanax are both commonly abused drugs. Cocaine is considered a stimulant or an “upper” while Xanax has an opposing effect making this the perfect drug combination for meanwhile at the same time, it is extremely dangerous and potentially lethal. 

When you combine cocaine and Xanax, you feel the side effects for both consecutively and this can lead to a heavier addiction to both substances, higher risk for overdose, harsher side effects, and possible death or coma. 

In a similar fashion, combining these drugs also increase negative mental health effects such as irritability, or depression. Likewise, there is a higher chance of an individual committing suicide when combining cocaine and Xanax. 

What is Cocaine?

Cocaine is a powerful stimulant drug that is used by over 1.5 million individuals each year. Cocaine is generally taken orally by snorting, rubbing it on the gums directly, or smoking and has also been known to be injected into veins. 

According to the National Institute on Drug Abuse, any form of the use of cocaine lead to heart attacks, seizures, and death.

Cocaine works by activating the reward pathway specifically in the midbrain region called the ventral tegmental area and cocaine also works by controlling emotions and motivations because it is so addictive and releases dopamine in the brain making you want to continue to use. 

Some Common Side Effects of Coke

Cocaine is powerful and addictive while also very dangerous on its own and when using other substances together. Due to cocaine use being so high in childbearing aged women, it’s important to note that when using cocaine while pregnant, there can be many risks involved such as maternal migraines, seizures, miscarriage, and premature labor. 

These are some of the symptoms of using cocaine

Short Term Effects of Cocaine Use:

  • Increased body temperature
  • Dilated pupils
  • Constricted blood vessels
  • Possible violent behaviour
  • Possible sudden death
  • Headaches
  • Seizures
  • Strokes

Long Term Effects of Cocaine Use:

  • Withdrawal
  • Tolerance
  • Irritability
  • Restlessness
  • Paranoia
  • Psychosis
  • Loss of sense of smell
  • Nosebleeds

What is Xanax?

Similar to cocaine, Xanax is also a powerful and addictive drug. On the other hand, it differs from cocaine because it is a benzodiazepine that relaxes you rather than excites you. 

Xanax is taken orally and works by calming down your central nervous system, immediately relieving panic and anxiety symptoms and making you feel at ease and in many cases drowsy. 

Individuals generally are prescribed Xanax to relieve anxiety and panic disorders and are not looking to become addicted. Over time, tolerance of the drug becomes harder to manage and withdrawal symptoms set in. Because of this, these individuals become reliant on Xanax and start to take more than prescribed. 

Long term use of Xanax can change the way the brain works without the drug in effect. Xanax can control our mood, emotional responses, thought processes, memory, and more. 

Some Common Side Effects of Xanax

Xanax is highly addictive but even though it is dangerous and addictive, more than 17 thousand people are prescribed Xanax for anxiety and panic disorders. Xanax addiction is on the rise, and it is not always from a prescription. Young adults and even teens have been known to be addicted because Xanax is so easy to obtain either by friends or family who are prescribed it. 

What are some of the side effects of using Xanax?

  • Violent behaviour
  • Weight Loss
  • Binge Eating
  • Lethargy
  • Weight gain
  • Forgetfulness
  • Speech problems
  • Loss of coordination
  • Concentration loss
  • Risky behaviours
  • Depression
  • Suicide
  • Irritability
  • Mood swings
  • Hallucinations
  • Paranoia
  • Delusions
  • Dementia

In contrast, Xanax can be medically helpful for individuals with severe alcohol withdrawal or seizure disorders.

How do Cocaine and Xanax Interact?

Cocaine and Xanax used together can create powerful euphoric feelings and almost a push and pull of ups and downs that relax you as well as gives you energy. Both Cocaine and Xanax are fast acting and the interaction in the body doesn’t last very long, leading to more and more use. 

There is no amount of Cocaine and Xanax taken together that is safe, even using these drugs on their own can lead to death or long-term adverse effects to the brain and body as well as social aspects like interpersonal relationships, work, school, etc. 

Why is it Common for People to Mix Cocaine and Xanax?

Oftentimes, individuals with a substance abuse disorder will mix other drugs with their particularly favourite drug to feel more effects. It’s very common for people to use cocaine, and it’s also very common for people to sue Xanax.

Mixing the two drugs have a powerful effect making you feel energetic, content, and happy but these effects only last for so long.The effects wear off and you become agitated and want to do more. Mixing cocaine and Xanax is common because cocaine is an upper, and Xanax is a downer so when used there is a balance of highs and lows during the initial short lasting high. 

What Happens when you Mix Cocaine and Xanax?

Some of the biggest risks involved with mixing cocaine and Xanax is an increased tolerance, dependence, and addiction that can be deadly. Tolerance happens when your body becomes used to a substance resulting in you needing to take more of it to feel the effects. 

Dependence occurs when you are taking the drug constantly to avoid withdrawal symptoms while addiction occurs when you are using the substances to cope with no regards to the negative symptoms. 

What are the withdrawal symptoms of cocaine and Xanax?

  • Depression
  • Suicidal thoughts
  • Anxiety
  • Insomnia
  • Changes in body temp and heart rate
  • Hallucinations
  • Restlessness
  • Trouble feeling pleasure
  • Mental cloudiness
  • Agitation
  • Extreme psychosis
  • Seizures

Mixing Cocaine and Xanax together can have severe lasting impacts to your cognitive functions as well as body movements and in many cases lead to death. It is never a good idea to mix substances especially substances like cocaine or Xanax that can drop your respiratory system to very low levels. 

The Opposing Effects of Xanax and Coke

Abusing Xanax gives you feelings of severe drowsiness and feelings of contentment and an overall sense of calm. Cocaine abuse brings on feelings of excitement, alertness, and sociability. These opposing effects are consequently the reason for addiction of cocaine and Xanax together. 

What are the signs of overdose with cocaine and Xanax use?

  • Extreme mental confusion 
  • Irregularities in heart rate, blood pressure, body temp, and breathing
  • Nausea and vomiting 
  • Balance and coordination issues
  • Loss of consciousness or coma

If you ever witness these symptoms on someone you should immediately call 911. Knowing the signs and symptoms of an overdose can potentially save a person’s life. 

How to find the Best Rehab Center for Xanax and Coke Abuse Treatment

Have you recently started using cocaine and Xanax together and want to get help? Maybe you are a long-time user who is approaching rock bottom in your addiction and want to get clean. It is so important to understand that you are not a bad person for having a drug addiction; addiction is a common way people cope or to feel relief from pain whether it be physical pain, emotional pain, trauma, PTSD, and more. 

Combating addiction takes determination and willingness to change, but it is absolutely possible. Now that you are ready to fight your addiction, you may be wondering how to find the best rehab center for Xanax and cocaine abuse treatment and may also be asking what the best drug addiction treatment programs near me are. 

Valley Detox is the first step to your treatment plan and is a great option for Cocaine and Xanax detox. Valley Detox is ready to serve you whether it’s your first detox, or you have been through previous detoxes in the past.  Contact Us on 1-844-402-3505 or visit our website for more information on detoxing from cocaine and Xanax .


The Recovery Village Palm Beach at Baptist Health. 2021. Dangers of Mixing Xanax and Cocaine | The Recovery Village Palm Beach at Baptist Health. [online] Available at:

National Institute on Drug Abuse. 2021. What is Cocaine? | National Institute on Drug Abuse. [online] Available at:

Serenity at Summit. 2021. Xanax & Cocaine: Can You Mix Them Safely? – Serenity at Summit. [online] Available at:

American Addiction Centers. 2021. Xanax Abuse: Symptoms and Signs | American Addiction Centers. [online] Available at:

American Addiction Centers. 2021. Xanax: Side Effects, Dangers & Long-Term Impacts. [online] Available at: